Premium Marriott Hotels in Lively Downtown Greenville

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Greenville is a vibrant city nestled in the center of the Upstate region, renowned for its charming downtown area teeming with cultural attractions, dining gems, and picturesque parks. At the heart of this bustling cityscape lie the Marriott hotels in downtown Greenville, offering a luxurious and convenient accommodation option for visitors seeking comfort and style. With their impeccable service and prime locations, Marriott hotels provide the perfect base for exploring all that Greenville has to offer.

From the moment you step into the inviting lobby of a Marriott hotel in downtown Greenville, you are greeted with modern amenities, elegant decor, and a warm Southern hospitality that sets the tone for a memorable stay. Whether you're in town for a business trip, a weekend getaway, or a family vacation, these hotels cater to all your needs, ensuring a seamless blend of comfort and convenience. With spacious rooms, plush bedding, and top-notch facilities, Marriott hotels redefine hospitality in the lively heart of Greenville.

As the sun sets over the stunning skyline of downtown Greenville, the Marriott hotels come to life, offering guests a perfect retreat after a day of exploring the city's vibrant arts scene, dining hotspots, and natural beauty. Whether you choose to unwind with a cocktail at the rooftop bar, savor a delicious meal at the onsite restaurant, or simply relax in the comfort of your well-appointed room, the Marriott hotels in downtown Greenville guarantee a rejuvenating experience that will leave you wanting to return again and again.

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Our Top 9

(Sorted by rating & number of reviews)

1. The Skylight Hotel
2. Tru By Hilton Greenville
3. Holiday Inn Express And Suites Greenville
4. Days Inn By Wyndham Greenville Ms
5. Harlows Casino Resort And Spa
6. Greenville Inn & Suites
7. Econo Lodge By Choice Greenville
8. Americas Best Value Inn & Suites Greenville
9. Rodeway Inn

Top Luxury Marriott Hotels Downtown Greenville SC

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Greenville
Dec 31, 2025 - Jan 01, 2026

The Skylight Hotel

8.4

Good

(90 Reviews)

+ 22 photos
Situated in the center of downtown Greenville boasts luxurious rooms with breathtaking city views and sophisticated design elements. Guests can indulge in a fine dining experience at the hotel's restaurant, offering a culinary journey through local flavors and international cuisine. The Skylight Hotel is the epitome of luxury, providing a tranquil retreat amidst the vibrant energy of the city.
Address: 745 Washington Avenue Suite B
Rating: Good 8.4 (90 Reviews)
Rooms: 15
Price: From 99$

Tru By Hilton Greenville

7.6

Good

(328 Reviews)

+ 34 photos
Tru By Hilton Greenville is a modern and stylish hotel that caters to families with its spacious rooms and vibrant communal spaces. The hotel's family-friendly amenities include a game room, outdoor seating area, and complimentary breakfast options for guests of all ages. With its contemporary design and focus on comfort, Tru By Hilton Greenville is an excellent choice for family travelers seeking a fun and relaxing stay in downtown Greenville.
Address: 600 Rayner Road
Rating: Good 7.6 (328 Reviews)
Rooms: 84
Price: From 161$

Best Budget-Friendly Marriott Hotels Downtown Greenville SC

For travelers seeking affordability without compromising on quality, the budget-friendly Marriott hotels in downtown Greenville SC offer a comfortable and convenient stay experience. These hotels provide excellent value for money, with clean and cozy accommodations and a range of amenities to ensure a pleasant stay at a reasonable price point.

Holiday Inn Express And Suites Greenville

+ 44 photos
Experience a seamless blend of comfort and elegance at Holiday Inn Express And Suites, where modern amenities meet Southern charm. The spacious suites are tastefully decorated and equipped with all the necessary conveniences for a relaxing stay. Guests can start their day with a complimentary breakfast buffet and unwind in the evening at the hotel's fitness center or outdoor patio.
Address: 3090 Highway 82 East
Rooms: 73
Price: From 169$

Days Inn By Wyndham Greenville Ms

5.6

Good

(413 Reviews)

+ 50 photos
Days Inn By Wyndham Greenville offers comfortable and affordable accommodations for families visiting downtown Greenville. The hotel's family rooms provide ample space for parents and children to relax and unwind after a day of exploring the city. Guests can enjoy the hotel's outdoor pool and complimentary breakfast, making it a popular choice for family vacations.
Address: 2701 Highway 82 East
Rating: Good 5.6 (413 Reviews)
Rooms: 120
Price: From 73$

Family-Friendly Marriott Hotels Downtown Greenville SC

For families traveling to Greenville, the family-friendly Marriott hotels in downtown Greenville SC offer a welcoming and accommodating stay experience. These hotels cater to the needs of both parents and children, providing spacious accommodations, kid-friendly amenities, and convenient access to family-oriented attractions in the city.

Harlows Casino Resort And Spa

+ 28 photos
Harlows Casino Resort And Spa is a unique boutique hotel in downtown Greenville that offers a luxurious and entertainment-packed stay experience. The hotel features elegant rooms, a full-service spa, and a world-class casino, providing guests with endless entertainment options. With its distinctive ambiance and upscale amenities, Harlows Casino Resort And Spa is the perfect choice for travelers looking for a boutique hotel experience in downtown Greenville.
Address: 4280 Harlows Blvd
Rooms: 105
Price: From 119$

Greenville Inn & Suites

8.1

Good

(117 Reviews)

+ 56 photos
Greenville Inn & Suites offers a family-friendly stay experience in downtown Greenville, with spacious suites and convenient amenities for guests of all ages. The hotel's indoor pool and fitness center provide entertainment and relaxation options for families, while the complimentary breakfast ensures a nourishing start to the day. With its central location and focus on family comfort, Greenville Inn & Suites is a top choice for family vacations in Greenville.
Address: 211 South Walnut Street
Rating: Good 8.1 (117 Reviews)
Rooms: 40
Price: From 89$

Unique Boutique Marriott Hotels Downtown Greenville SC

For travelers seeking a one-of-a-kind stay experience, the unique boutique Marriott hotels in downtown Greenville SC offer a distinctive and charming ambiance that sets them apart from traditional accommodations. These boutique hotels combine personalized service, stylish decor, and a touch of local flair to create a memorable and intimate stay experience for guests looking for something different.

Econo Lodge By Choice Greenville

4.6

Good

(5 Reviews)

+ 47 photos
Econo Lodge Greenville offers budget-conscious travelers a comfortable stay in the heart of downtown Greenville. The hotel's cozy rooms are equipped with essential amenities and provide a peaceful retreat after a day of exploring the city. Guests can enjoy complimentary breakfast and coffee to kickstart their day before setting out to discover Greenville's attractions.
Address: 3080 Us 82 E.
Rating: Good 4.6 (5 Reviews)
Rooms: 77
Price: From 169$

Americas Best Value Inn & Suites Greenville

5.7

Good

(93 Reviews)

+ 19 photos
Conveniently located near downtown Greenville's attractions, Americas Best Value Inn & Suites offers affordable accommodations with easy access to the city's key landmarks. The hotel's clean and comfortable rooms provide a restful environment for guests to unwind after a day of sightseeing. With its budget-friendly rates and convenient location, Americas Best Value Inn & Suites is a popular choice for value-conscious travelers.
Address: 2700 Highway 82 East
Rating: Good 5.7 (93 Reviews)
Rooms: 80
Price: From 66$

Pet-Friendly Marriott Hotels Downtown Greenville SC

For travelers who prefer to bring their furry companions along, the pet-friendly Marriott hotels in downtown Greenville SC offer a welcoming stay experience that caters to both guests and their four-legged friends. These hotels provide pet-friendly accommodations and amenities to ensure a comfortable and enjoyable stay for pets and their owners alike.

Rodeway Inn

2.5

Good

(4 Reviews)

+ 49 photos
Rodeway Inn provides a budget-friendly stay option in downtown Greenville, offering clean and comfortable rooms at affordable rates. Guests can take advantage of the hotel's complimentary breakfast and Wi-Fi, ensuring a hassle-free stay experience. With its convenient location and cost-effective pricing, Rodeway Inn is a practical choice for travelers looking to explore Greenville on a budget.
Address: 137 N. Walnut Street
Rating: Good 2.5 (4 Reviews)
Rooms: 99
Price: From 79$

Business-Friendly Marriott Hotels Downtown Greenville SC

For business travelers looking for a seamless stay experience in downtown Greenville, the business-friendly Marriott hotels in the area cater to their specific needs with convenient amenities and services tailored for corporate guests. These hotels provide a comfortable and productive environment for business travelers to work, network, and unwind during their stay.

Romantic Getaway Marriott Hotels Downtown Greenville SC

For couples seeking a romantic escape, the Marriott hotels in downtown Greenville SC offer a selection of intimate and enchanting properties that provide the perfect setting for a memorable romantic getaway. These hotels combine luxurious accommodations, personalized service, and romantic amenities to create a magical ambiance for couples looking to celebrate love and romance.